Republican presidential front-runner Donald Trump and former Florida Gov. Jeb Bush (R) sparred in an early presidential-debate exchange during which Trump confronted the audience multiple times.

Bush brought up Trump's name unprompted in order to question the real-estate developer's plans to combat the Islamic State in the Middle East. Bush said it was "ludicrous" to support Russia helping the US out in Syria, as Trump has done.

"Let me just tell you this: Jeb is so wrong. Jeb is absolutely so — ah," Trump began.

A chorus of booed in the audience interrupted Trump, who then suggested that the crowd was stacked with pro-Bush elites in the GOP establishment. 

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